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GLP 1 and IVF: what the trials show Thinking about a GLP 1 before IVF? Most of the data comes from PCOS fertility trials. If your clinic brought up your weight before IVF, here are the numbers. All small randomized trials in women with PCOS, each comparing a GLP-1 with metformin. Liragluti
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does loose skin on glp-1 depend on how much weight you lose A survey of 1,226 weight-management patients in Dermatology and Therapy sorted people by how much body weight they lost. Above 20% lost, 72% reported skin sagging, compared with 15% of people who lost under 10%. Hair loss, facial volume a
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GLP 1 and IVF: what the trials show Thinking about a GLP 1 before IVF? Most of the data comes from PCOS fertility trials. If your clinic brought up your weight before IVF, here are the numbers. All small randomized trials in women with PCOS, each comparing a GLP-1 with metformin. Liragluti
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why am i not losing as much weight as the trials A new review in the Journal of Diabetes compared 127 trials with 26 real-world studies. People who stayed on and reached the trial doses lost about what trial participants lost. The big gap shows up when you count everyone prescribed, and in Denmark
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GLP1 and pregnancy: why timing matters If you're stopping a GLP1 before pregnancy, the timing finding here is worth knowing. In one study, gestational diabetes and GLP1 stop timing were linked. A new narrative review in BJOG pulled together what's known about GLP-1 exposure from before concep
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HHS just opened the door for six unapproved peptides
On October 28, HHS said it won't take action against licensed pharmacies that compound six peptides: BPC-157, TB-500, KPV, MOTS-c, Semax and Epitalon. That's enforcement discretion. Nothing got approved, nothing was added to the official bulks list, and the policy can be pulled at any time. I
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Why your peptide will probably never be FDA approved
People ask me all the time when BPC-157 is going to get approved. My honest answer is probably never. Here's why. A peptide is a short chain of amino acids. Think of amino acids as letters and a peptide as a word. Federal law draws the line at 40. At 40 amino acids or fewer, it's regulated as
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Switching telehealth providers after nearly 3 years on compounded meds. Choosing a telehealth provider is hard and there’s so many different variables, especially when the GLP-1 market is flooded right now. I’m now a @GobyMeds patient AND I work there as Social Media Director and Affiliate
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Switching telehealth providers after nearly 3 years on compounded meds. Comparing telehealth providers is basically my whole channel, so this one’s personal: I’m now a @GobyMeds patient AND I work there as Social Media Director and Affiliate Manager. I went through their full intake and got my firs
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Replying to @Beniciaa GLP-1 and pregnancy: a new meta-analysis pooled 2.1 million pregnancies to ask what happens when someone conceives while on one of these medications. 8,325 of those pregnancies were exposed around conception. No clearly detectable increase in miscarriage, birth defects, pre
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GLP-1s and your skin — 1,226 patients surveyed. New data published this month asked people on medical weight management what actually happened to their skin, hair, and muscle. 61.9% reported at least one concern: skin sagging 37.7%, facial volume loss 29.2%, hair loss 28.9%, worsened skin qualit
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Why does everything taste weird on a GLP-1? A study of nearly 900,000 people found a real signal — and one number in it is about to get misquoted everywhere. What food changed for you? #foodnoise #glp1community #tastebuds #healthnews #glp1sideeffects
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Replying to @Arlyn Porras Is retatrutide out there? What 652 medical records show. A preprint posted August 18 searched a 29-million-patient health record network for every mention of retatrutide, the unapproved triple agonist. 652 people had confirmed exposure, and among those with a documented s
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Can you take a GLP-1 with other medications? Two new papers say the pairing is already happening — with antipsychotics, and after heart transplant. The assumption underneath it hasn't been tested yet. #mentalhealth #hearttransplant #glp1community #medicalresearch #cancer
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Replying to @Laykn Smith Gut bacteria and GLP-1s — a review published July 2026 asks whether your microbiome helps decide how well these drugs work for you. In the most cited human study (52 patients with T2D), people who responded well had more diverse gut bacteria and more short-chain-fatty-acid
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What is amylin? Not a GLP-1 — a different pancreatic hormone that's being paired with them. Here's what the trial data actually shows. #amylin #obesitymedicine #glp1community #cagrilintide #pharmaceuticalindustry
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GLP-1s and birth control — two of these tell you, in the label, to change your contraception when you start. Tirzepatide's label says use may reduce the efficacy of oral hormonal contraceptives due to delayed gastric emptying, and advises switching to a non-oral method or adding a barrier method fo
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Replying to @Shelbs What happens if you get pregnant on a GLP-1? Across ~50,000 exposed pregnancies there is no reproducible signal for major birth defects — and in the anchor study, malformation risk tracked the underlying diabetes far more than the drug. Separately: semaglutide's labels say disco
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Replying to @Debra Stark Do GLP-1s affect milk supply? Nobody knows — and I mean that literally. Zero published studies. Hashtags: #breastfeeding #lactation #postpartum #glp1community #medicalresearch
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Food noise finally has a scientific definition. You've heard the term everywhere, that constant mental chatter about food running in the background all day. Up until now clinicians and researchers didn't have a shared definition, so nobody could actually measure it or prove it changes. A new paper
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