Managing diabetic ketoacidosis effectively requires not only addressing high blood glucose but also meticulous monitoring of electrolytes, especially potassium (K⁺). In clinical practice, I’ve seen how essential it is to track potassium levels closely during insulin therapy. Insulin helps lower blood sugar but also drives potassium into cells, potentially causing dangerous hypokalemia if potassium levels aren’t adequately replaced. In one case, a patient’s potassium dipped below 3.3 mmol/L shortly after starting insulin. Immediately holding insulin and initiating potassium replacement prevented cardiac complications that can arise from severe hypokalemia. This underscores why the anion gap closure and pH normalization, rather than just blood glucose lowering, are critical endpoints in DKA management. I also emphasize that potassium replacement must be carefully tailored based on lab values and clinical signs. Frequent lab monitoring every 2-4 hours allows for safe titration of electrolytes and insulin doses. A failure to recognize low potassium during insulin infusion can lead to fatal arrhythmias. For nursing students and new clinicians, practicing these principles in simulations or clinical questions improves decision-making skills. Resources with application-style questions on DKA and electrolyte management can deepen understanding. Maintaining a focus on potassium dynamics alongside glucose and acid-base balance is a key to successful, safe care during DKA treatment.