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Correction of Hyperkalemia 📚

🧠 meaning

Hyperkalemia = a condition where blood potassium levels are greater than 5.0 mEq / L.

It's considered dangerous because potassium has a direct effect on the conduction of the heart.

➡ Arrhythmia or cardiac arrest can occur.

⚡ common cause.

1.Drive K Out Less - Kidney Failure, Use ACEI / ARB Group Drug, Spironolactone

2.K Move out of the cell - acidosis, muscle injury / breakdown (rhabdomyolysis)

3.Get K Exceed - from food or water substance with high K, mass blood feeding

❤️ found ECG.

• Tall peaked T wave

• Long interval PR

• Wide QRS

• It can become a sine-wave pattern → cardiac arrest.

🚨 Principles of Hyperkalemia Treatment

The treatment is divided into 4 main steps, according to the goal "Prevent the heart - Move potassium - Expel potassium - Solve the cause."

🩺 1. Prevent cardiac arrest.

Reduced the effect of K on heart muscle, but did not reduce the actual K level.

→ Calcium Gluconate 10% (10 mL IV in 2-5 minutes)

• Acting within 1-3 minutes, lasts ~ 30-60 minutes

• Use in the presence of abnormal ECG or K ≥ 6.5 mEq / L

• Do not inject muscles / Do not accompany NaHCO along the same way

💡. If there is no ECG change →, there is no need to give.

🧬 2.Move potassium into cells (Shift K into cells)

To temporarily reduce the level in the blood.

- Insulin + Dextrose

Regular insulin 10 units IV + 50% Dextrose 50 mL

Insulin allows K to enter the cell

- Obi ❣ -agonist (Salbutamol neb.)

10-20 mg nebulizer

Stimulate Na / K pump

- NaHCO (in metabolic acidosis)

50 mEq IV slow

Add pH → K to cell

💧 3. Expel potassium from the body (Remove K from body)

Real K level reduction

- Loop diuretic (Furosemide) increased urinary K driving

Must see if the patient can urinate.

- Sodium polystyrene sulfonate (Kayexalate) binds K in intestine, excretes through feces, acts slowly (2-6 hours)

- Hemodialysis, the fastest and surest method. Use in case of kidney failure or treatment resistance.

🧩 4.Fix the cause of high K

• Stop K-added drugs (ACEI, ARB, Spironolactone, KCl supplements, etc.)

• Treatment of renal failure / acidosis

• Adjust food, reduce potassium

📋 Simple Remember Summary "Hyperkalemia Treatment Procedure Sequence"

1️⃣ Protect heart → Calcium gluconate

2️⃣ Shift K into cells → Insulin + Dextrose / Salbutamol / NaHCO

3️⃣ Remove K from body → Furosemide / Kayexalate / Dialysis

4️⃣ Find and fix cause.

# Professional nurse # Nurse review # Nurse knowledge

2025/10/24 Edited to

... Read moreภาวะโพแทสเซียมในเลือดสูงหรือ Hyperkalemia เป็นภาวะที่ต้องได้รับการดูแลและรักษาอย่างเร่งด่วน เนื่องจากโพแทสเซียมมีผลกระทบโดยตรงต่อการนำกระแสไฟฟ้าของกล้ามเนื้อหัวใจ หากไม่รักษาอย่างเหมาะสม อาจก่อให้เกิดภาวะหัวใจเต้นผิดจังหวะ หรือแม้กระทั่งหัวใจหยุดเต้นได้ สภาพนี้เกิดขึ้นได้จากหลายสาเหตุหลักที่พบบ่อย ได้แก่ ภาวะไตวายซึ่งทำให้ร่างกายขับโพแทสเซียมได้น้อย ยาในกลุ่ม ACEI/ARB หรือสไปโรรโนแล็คโทนที่เพิ่มระดับโพแทสเซียมในเลือด ภาวะกรดในร่างกายที่ทำให้โพแทสเซียมเคลื่อนออกจากเซลล์ รวมถึงการได้รับโพแทสเซียมมากจากอาหารหรือสารน้ำหรือการให้เลือดจำนวนมาก การวินิจฉัยภาวะนี้นอกจากการตรวจค่าระดับโพแทสเซียมในเลือดแล้ว ยังสามารถสังเกตจากคลื่นไฟฟ้าหัวใจ (ECG) ที่มีลักษณะเฉพาะ เช่น T wave ที่สูงและแหลม (Tall peaked T wave), ระยะ PR interval ที่ยาวและ QRS ที่กว้าง หากปล่อยไว้จะเกิดรูปแบบ sine-wave ซึ่งเป็นสัญญาณเตือนว่าหัวใจอาจหยุดเต้นได้ การรักษาภาวะโพแทสเซียมสูงควรเน้นตามลำดับขั้นตอน โดยขั้นตอนแรกคือการป้องกันไม่ให้หัวใจหยุดเต้น เช่น ให้ Calcium Gluconate ซึ่งช่วยลดผลกระทบของโพแทสเซียมต่อกล้ามเนื้อหัวใจ ถึงแม้จะไม่ลดระดับโพแทสเซียมจริง ๆ ขั้นตอนที่สองคือการย้ายโพแทสเซียมเข้าสู่เซลล์โดยใช้ยาอินซูลินกับดิกซ์โตรส, β₂-agonist หรือ Sodium bicarbonate ในผู้ป่วยที่มีภาวะ metabolic acidosis ขั้นตอนที่สามคือการขับโพแทสเซียมออกจากร่างกายจริง ๆ โดยการใช้ยาขับปัสสาวะชนิด Loop diuretic เช่นฟูโรเซไมด์ หากผู้ป่วยยังขับปัสสาวะได้ หรือใช้ยาจับโพแทสเซียมในลำไส้ เช่น Sodium polystyrene sulfonate (Kayexalate) ซึ่งออกฤทธิ์ช้า หรือในกรณีที่ไตวายรุนแรง อาจต้องใช้วิธีฟอกเลือด (Hemodialysis) ซึ่งเป็นวิธีที่รวดเร็วและได้ผลชัดเจนที่สุด สุดท้ายคือการแก้ไขสาเหตุที่ทำให้โพแทสเซียมสูง เช่น การหยุดใช้ยาที่เพิ่มโพแทสเซียม ปรับการรักษาภาวะไตวายและภาวะกรด รวมถึงการควบคุมอาหารเพื่อลดการรับโพแทสเซียมเกินความจำเป็น การให้ความรู้ผู้ป่วยและทีมสุขภาพเกี่ยวกับการดูแลภาวะนี้เป็นสิ่งสำคัญ ในทางปฏิบัติเมื่อพบภาวะ Hyperkalemia ควรประเมินอาการและตรวจคลื่นไฟฟ้าหัวใจอย่างละเอียด เพราะการเปลี่ยนแปลงบน ECG เป็นตัวชี้วัดที่สำคัญในการตัดสินใจให้การรักษาอย่างเร่งด่วน เพื่อป้องกันภาวะแทรกซ้อนรุนแรงที่จะเกิดขึ้นจากโพแทสเซียมเลือดสูงอย่างมีประสิทธิภาพ

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