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What is the difference between GFR and eGFR?

← I can't hear it now 💡

People who want to study in free time 📚

What is the difference between GFR and eGFR 🤔

Test to know the degree of kidney function 🩸

With other data such as BUN · Cre

Let's figure ✊✨

_ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _

i'm ichan, a surgical nurse 👩‍⚕️

Busy ward nurse 💉

Flapping every day,

Even if there is something I do not understand, I can not afford to investigate... 💦

At the end of work,

I don't have the energy to study 😣

But it's okay! ✨

Just looking here for one minute a day, confidence in work ⤴️

Learn quickly in the gap time,

Let's play well on holidays 🏖️📚

We are not responsible for any loss or damage related to this post, and we do not explain everything.

2025/11/28 Edited to

... Read more実際の現場でつまずきやすいのが、「eGFRが低い=すぐ腎不全?」と短絡しそうになるところでした。私は採血のCreだけ見て焦ったことがあるのですが、eGFRは“推定”で、年齢・性別・Creから計算される値なので、体格や筋肉量の影響を受けます。 特に「痩せ型」で筋肉量が少ない人はCreが低めに出やすく、eGFRが“良く見える”方向にブレることがあります。逆に、筋肉量が多い人はCreが高めになりやすく、eGFRが低めに見えることも。なので、eGFR単体で断定せず、体型(痩せている/がっしり)や栄養状態、浮腫、脱水の有無を一緒に見ておくと納得しやすかったです。 基準値は施設や計算式で多少差がありますが、ざっくり「eGFR 60未満が3か月以上続く」場合はCKDを疑う目安になります。分類でいうとG3a(45〜59)は“軽〜中等度低下”で、薬剤量調整や造影剤前後の注意が必要になることが多い印象です。G4(15〜29)では透析や腎代替療法の説明が話題に上がりやすく、急変(AKI)か慢性(CKD)かの見極めも重要になります。 「糸球体濾過機能を評価する項目は?」と聞かれたら、基本はGFR/eGFRが中心。ただ、私はいつもセットで①尿蛋白(蛋白尿は腎障害のサイン)②尿潜血(腎炎などの示唆)③BUN(蛋白分解産物で脱水や出血でも上がる)④Cre(腎排泄でGFRの代用指標)を並べて見ています。BUN/Cre比が高いときは脱水や消化管出血など“腎前性”を疑うなど、背景を考えるとアセスメントがつながります。 最後に、透析関連でSLEDという言葉を見かけたら、これは「持続透析(CRRT)」と「間欠的血液透析(IHD)」の中間のような位置づけで、ゆっくり長めに行う透析方法です。循環動態が不安定な患者さんで検討されることがあり、「腎機能がどの段階(G分類)で、なぜその方法が選ばれているか」をeGFRや尿量、電解質(Kなど)と合わせて確認すると理解しやすかったです。

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