Disease

🧠 depressants cause Thalamus, a station that filters negative signals, to let go of it all without filtering.

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The brain is like a big capital with a full functional center, connected by an endless train of cobwebs.

But there are some "routes" that are considered high-priority, that do not run directly from the source to the destination, that go through a "giant railway station" with a variety of platforms.

📍 this station is called Thalamus, the part of the brain that has the most path to connect signals and "filter signals."

[🔎 Thalamus works like this.]

1️⃣ Get the signal and send it up to the report (Bottom-up).

There are external world signs coming into the picture: image, sound, smell, touch, balancing.

→ Each receptor converts to an electrical signal.

→ Enter Thalamus Station, separate platforms (except smell)

→ The thalamus passes on to the Cerebral cortex, while there may be a slight filter.

We will call the procedure by which the thalamus emits incoming signals and up the cortex brain report "bottom-up."

2️⃣ is screened by the cortex (Top-down control).

After the cortex brain is processed,

→ Recognized as more or less

→ Signaling backwards (Cortico-thalamic fibre)

→ Restrain thalamus to filter out more signals

→ Lighten the next reception

We will call the top step (Cortex) sending the delay command to Talamus "Top-down control."

3️⃣ Bottom-up and top-down control also occur with internal signals.

Emotions, negative memory, are triggered.

→ Enter Talamus Station MDT / Pulvinar / ILN Platform

→ Adjust the signal and then pass it on to memory and emotional processing centers such as Amygdala, Hippocampus, ACC, OFC are also bottom-up mechanisms.

→ We perceive memory and feel that emotion.

→ Centers send back signals down the thalamus (Top-down control)

→ Thalamus lighten the new entry signal.

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🚦 or, more simply, Talamus is like a large checkpoint. If the above says that it is overly perceived, the checkpoint must be more rigorous. Send it gently.

[⚠️ in depressed people]

In depressed people, the thalamus station is creased. Bottom-up also occurs strongly, but there is almost no top-down.

📉. The result is

1️⃣ is too interested in the negative inside and out, because every signal sends to the abnormal thalamus and goes up to the center of perception, without the top-down restraining it.

2️⃣ a combo with a ruined Salient network center. Originally, this center would keep the switch from DMN to CEN. But in depression, this center does very little work in normal work, but! If it finds a negative thing, the result of number 1 with a severe bottom-up makes it pay attention to so many negative things that it can't be removed.

3️⃣ a phenomenon called Negative bias / Over-attention, because negative data streams are not braked, ambiguous things are emitted into the sad brain, negative bias.

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📌 The conclusion is that the brain of depression is not only easy to change to negative thinking, but the center that filters the signal does not work, making it negative for a long time and very stable.

To make Talamus back as beautiful as ever. Let's get into treatment and psychotherapy.