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Brianna | POTS & Recovery
Brianna | POTS & Recovery

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The image displays the title slide for a presentation, reading "POTS, COVID, AND PLATELETS: NEW FINDINGS CORROBORATE CLINICAL RESEARCH" in pink and white text on a yellow background with a pink border.
This slide, titled "POTS AND VIRAL ILLNESS," explains that POTS may be triggered by viral infections, with up to 80% of long-COVID patients meeting POTS criteria, highlighting platelets' role in the immune response.
Titled "PLATELETS AND SEROTONIN," this slide details that platelets store 99% of serotonin, and impaired storage can cause symptoms like hypotension, fatigue, dizziness, and headaches, noting POTS patients have fewer platelet dense granules.
Under the title "BLEEDING SYMPTOMS," this slide lists symptoms associated with platelet dense granule deficiency, including easy bruising, nosebleeds, gum bleeding, heavy menstrual bleeding, and prolonged bleeding after trauma.
The slide "STUDY GOALS" outlines the study's two purposes: validating platelet dense granule storage pool deficiency in POTS patients and comparing symptoms between Pre-COVID and Post-COVID POTS groups to link POTS to immunologic stressors.
Titled "WHO WAS STUDIED," this slide presents participant demographics, showing a high percentage of women in all groups (73-96%), consistent with POTS being most common in young, premenopausal Caucasian women.
The slide "ASSESSMENT TOOLS" lists the questionnaires used in the study: Bleeding Assessment Tool (BAT) for bleeding severity, Menses assessment for menstrual bleeding, Composite Autonomic Symptom Score (COMPASS-31) for dysautonomia, and clinical symptom measurement.
Under "STUDY FINDINGS," the slide reports that POTS groups had abnormal Bleeding Assessment Tool scores (≥5) and higher menstrual bleeding scores compared to controls, correlating with reduced platelet dense granule numbers.
The slide "ORTHOSTATIC INTOLERANCE AND CAUSES" defines orthostatic intolerance and lists proposed causes including viral illness, low serotonin levels, and autoantibodies, noting its prevalence and links to various morbidities.
Titled "MISDIAGNOSIS AND PREVALENCE," this slide explains that POTS is often misdiagnosed as anxiety due to subtle symptoms like fatigue and dizziness, affecting 1-3 million Americans and 65 million worldwide with Post-Acute COVID Syndrome.
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🩸 POTS, COVID & Platelets: New Research

Did you know that up to 80% of people with long-COVID symptoms meet the criteria for POTS (Postural Orthostatic Tachycardia Syndrome)? 💥 This new research shows how viral illness, serotonin storage in platelets, and immune system triggers all connect.

Symptoms like dizziness, fatigue, headaches, exercise intolerance, and even unusual bleeding patterns may not just be “in your head.” 🧠➡️🫀

This info helps explain why so many are being misdiagnosed with anxiety or panic disorder when in fact, their bodies are showing measurable changes.

Sharing this to raise awareness because millions are affected worldwide 🌍💛

#POTS #LongCOVID #ChronicIllness #InvisibleIllness #HealthTok

2025/9/16 Edited to

... Read moreRecent studies have shed light on the intricate relationship between long-COVID and Postural Orthostatic Tachycardia Syndrome (POTS), highlighting the complexity of symptoms that extend beyond typical viral recovery. POTS is a form of dysautonomia, where the autonomic nervous system malfunctions, leading to rapid heart rate upon standing, dizziness, and fatigue. This syndrome is now recognized to be present in up to 80% of long-COVID patients. One groundbreaking area of research focuses on serotonin storage in platelets. Platelets are small blood components that, besides their role in clotting, store serotonin, a key neurotransmitter influencing vascular tone and mood. Altered serotonin dynamics in platelets may contribute to the unusual bleeding patterns noted in some patients and play a role in the autonomic dysfunction seen in POTS. The immune system’s response to viral illness, such as COVID-19, appears to be a critical trigger that disrupts normal platelet function and serotonin regulation. This immune activation can cause systemic inflammation, which may lead to neurological symptoms like headaches and fatigue, as well as cardiovascular irregularities characteristic of POTS. Understanding these mechanisms is vital because many patients with POTS and long-COVID symptoms are often misdiagnosed with anxiety or panic disorders, as their symptoms overlap. However, the presence of measurable physiological changes emphasizes that these symptoms are rooted in tangible biological processes rather than purely psychological origins. This awareness is crucial not only for accurate diagnosis but also to develop more targeted therapies that address the root causes of symptoms. Patients experiencing these signs are encouraged to seek medical evaluation from specialists familiar with dysautonomia and long-COVID research. Globally, millions face the challenge of living with these invisible illnesses. Sharing updated scientific insights helps validate their experiences and promotes better understanding, acceptance, and support within healthcare and social communities.

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Erin

thank you❤️

2025/9/18
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